tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate - Names and Identifiers
Name | tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate
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Synonyms | 8-Boc-1,3-Dioxo-2,8-diazaspiro[4.5]decane tert-Duty 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate tert-Butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate TERT-BUTYL 1,3-DIOXO-2,8-DIAZASPIRO[4.5]DECANE-8-CARBOXYLATE 1,1-Dimethylethyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate - B6616 2,8-Diazaspiro[4.5]decane-8-carboxylic acid,1,3-dioxo-,1,1-diMethylethyl ester
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CAS | 752234-60-9
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InChI | InChI=1/C13H20N2O4/c1-12(2,3)19-11(18)15-6-4-13(5-7-15)8-9(16)14-10(13)17/h4-8H2,1-3H3,(H,14,16,17) |
tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate - Physico-chemical Properties
Molecular Formula | C13H20N2O4
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Molar Mass | 268.31 |
Density | 1.23±0.1 g/cm3(Predicted) |
Boling Point | 440.1±45.0 °C(Predicted) |
Flash Point | 219.949°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 11.72±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.534 |
tert-Butyl 1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxylate - Introduction
tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate is an organic compound with the formula C10H17NO4. It is a white solid with a special molecular structure. The following are some information about the properties, uses, preparation and safety of the compound:
Nature:
-Appearance: White solid
-Molecular mass: 223.25g/mol
-Melting point: about 35-38°C
-Boiling point: about 265°C
-Solubility: Soluble in organic solvents such as methanol, ethyl acetate and dichloromethane
Use:
- tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate can be used as a reagent in organic synthesis.
-It is often used to synthesize biologically active molecules, such as drugs and pesticides.
Preparation Method:
tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5] The preparation method of decane-8-carboxylate is relatively complicated, and it usually requires a multi-step reaction to synthesize. A common synthetic method involves the following steps:
1. react 1,8-diamine octane (1,8-diaminooctane) with subbutyl hydroperoxide (tert-butyl hydroperoxide) to give 1,3-dioxo -2,8-diazaspiro [4.5] decane.
2. 1,3-dioxo -2,8-diazaspiro[4.5]decane is reacted with chloroformate (acetyl chloride) to obtain the tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate.
Safety Information:
- tert-butyl 2,4-dioxo-3,8-diazaspiro[4.5]decane-8-carboxylate is an organic compound whose potential hazards and toxicity require careful handling.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Wear appropriate protective equipment such as gloves and goggles during use.
-Observe appropriate safety procedures and regulations during storage and handling.
-Detailed safety information and emergency measures can be found in the safety data sheet (MSDS) of the compound.
Last Update:2024-04-09 02:00:48